22q Syndrome and Constipation in Kids: What Parents Should Know

22q11.2 deletion syndrome (22q syndrome), also known asDiGeorge syndrome, is a genetic condition that can affect multiple systems in the body, including digestion.

Many kids with 22q experience chronic constipation, which can be frustrating for both kids and parents.

Understanding why constipation is common in 22q syndrome and how to manage it can make a significant difference in a kid’s comfort and well-being.

Why Do Kids with 22q Syndrome Experience Constipation?

Constipation is a frequent issue in kids with 22q syndrome due to several underlying factors:

1. Low Muscle Tone (Hypotonia)– Weak muscle tone, including in the gastrointestinal tract, can slow down digestion and bowel movements.

2. Gut Motility Issues – Some kids with 22q have reduced gut motility, meaning food moves more slowly through the intestines, leading to hard stools.

3. Feeding and Swallowing Difficulties– Kids with 22q may have difficulty eating a high-fiber diet, making it harder to maintain regular bowel movements.

4. Medication Side Effects – Some medications prescribed for heart conditions, seizures, or immune issues in kids with 22q can contribute to constipation.

5. Neurological Involvement– 22q syndrome can affect the nervous system, impacting the signals that regulate digestion and bowel movements.

Managing Constipation in Kids with 22q Syndrome

While constipation can be persistent in kids with 22q, several strategies can help promote regularity and improve digestive health:

1. Increase Fiber Intake

A diet rich in fiber can help soften stools and promote regular bowel movements. Some fiber-rich foods that may be easier for kids with 22q to tolerate include:

• Mashed sweet potatoes

• Pureed fruits (pears, prunes, applesauce)

• Blended vegetables (carrots, zucchini, squash)

2. Hydration Is Key

Ensuring kids drink enough water throughout the day is crucial for preventing constipation. If your little one struggles with plain water, electrolyte drinks or fruit-infused water can be good alternatives.

3. Probiotics and Prebiotics for Gut Support

Supporting a kid’s gut microbiome can help improve digestion. Growing Up Prebiotics, which contains Human Milk Oligosaccharides (HMOs), helps nourish beneficial gut bacteria like Bifidobacterium infantis, which plays a role in stool regularity.

4. Gentle Movement and Physical Activity

Encouraging movement, such as tummy time for babies or stretching and walking for older kids, can help stimulate digestion and bowel movements.

5. Establish a Bathroom Routine

Creating a consistent bathroom schedule, especially after meals, can help train the body to have more regular bowel movements.

Summary

Constipation is a common but manageable challenge for kids with 22q syndrome. Contributing factors include low muscle tone, gut motility issues, and dietary challenges, but strategies such as increasing fiber intake, hydration, probiotics, and a regular bathroom routine can make a big difference.