Health Benefits of Human Milk Oligosaccharides (HMOs) for Infants and Kids
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When it comes to supporting your kid’s health, we as dietitians often talk about essential nutrients like vitamins and minerals.
However, there’s an additional nutrient that’s often less talked about that’s equally important when it comes to the health and vitality of infants and kids - human milk oligosaccharides (HMOs).
Let’s review the role of human milk oligosaccharides in kids and how parents can get the benefits of HMO’s for their kid’s health.
What Are Human Milk Oligosaccharides (HMOs)?
Human milk oligosaccharides, or HMOs, are a type of complex carbohydrate found in human breast milk. T
hey are not digested, but instead serve as a prebiotic, which is nourishment for the beneficial gut bacteria in the microbiome. Prebiotics promote the growth of a healthy gut in infants and kids.
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How HMOs Benefit Kids' Digestion and Gut Health
Promotes a Diverse Gut Microbiome:
- HMOs promote the growth of beneficial bacteria such as Bifidobacterium while inhibiting the growth of harmful pathogens. A diverse gut microbiome is associated with better digestion and a strengthened immune system
Reducing Inflammation in the Gut
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HMOs help maintain a balanced gut environment by producing short chain fatty acids after fermenting in the gut, producing anti-inflammatory effects in the digestive tract. This can be particularly beneficial for kids with digestive sensitivities or conditions like irritable bowel syndrome because chronic inflammation has been associated to perpetuate the symptoms of IBS. [1, 2].
Strengthening Immune Function
- 80% of our immune cells live in the gut microbiome [4]. HMOs directly influence immune cells in the gut by changing the composition of the gut microbiota [5]. This can help build and strengthen the overall immune system of your little ones.
Supports Early Microbiome Development in Infants
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The early-life microbiome development has a strong impact on both short-term and long-term health [6]. Current literature supports that infant consumption of HMO’s through supplementation can help mimic the benefits to those of breastfed infants to support healthy growth and development.
Where Can Infants and Kids Get Human Milk Oligosaccharides?
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Breast Milk: The richest and most direct source of HMOs is human breast milk. Mothers naturally produce HMOs to nourish their infants.
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HMO Supplements: HMO supplements are available mostly in powder forms. These supplements are designed to provide the benefits of HMO to kids beyond the breastfeeding age. When looking for supplements, it’s best to choose ones that are third-party tested to ensure that you kiddos get a high-quality and safe product. If your kids experience persistent digestive issues, please consult a pediatrician for guidance and support before starting any new supplements.
Begin Health Expert Tip It’s tasteless, textureless, and an easy way for kids to get the benefits of human milk oligosaccharides in their diet.
Can Kids Safely Consume Human Milk Oligosaccharides?
Studies on HMOs have consistently found that HMO supplementation was safe and well tolerated in both infants and kids.
The infant studies reported an overall positive shift in outcomes towards those observed in breastfed infants, including stool characteristics, gut microbiome composition, and intestinal immune markers [6].
Summary
Human milk oligosaccharides are the third most abundant component of human breast milk, which is often recognized as the gold standard of a source of nutrition for infant health. Consuming HMO’s can help benefit kids and infants by supporting both digestive health and immunity.
While breastfeeding is the most direct source of HMOs, supplements like Growing Up Prebiotics combined with a diverse, fiber-rich diet can also contribute to a healthier gut microbiome in kids and infants.

Author
May Zhu, RDN
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