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How to Choose a Baby Supplement: What Parents Need to Know

Medically Reviewed by May Zhu, RDN | Published April 16, 2025

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Walking through the baby aisle or scrolling online can be overwhelming. There are probiotics, prebiotics, vitamins, iron drops, omega-3s and each product claims to support your baby’s health.

But how do you actually choose the right supplement for your baby?

The truth is, babies have different needs depending on how they’re fed, their age, their birth experience, and even their poop patterns. Choosing the right supplement starts with understanding what your baby might be missing and what each supplement actually does.

Step 1: Know What Your Baby Might Need

Not every baby needs the same supplement. Here are a few factors to consider:

  • Breastfed vs. formula-fed:Breastfed babies often need extra vitamin D, while formula-fed babies may not. On the other hand, formula-fed babies may miss out on the prebiotics and good bacteria found in breastmilk.

  • C-section birth: Babies born via C-section may miss out on exposure to beneficial gut bacteria that babies born vaginally usually get. Some parents choose probiotic supplements to help support gut development [1].

  • Signs of constipation or digestive discomfort:If your baby is straining, skipping poops, or seems uncomfortable, a prebiotic or probiotic might help support regular digestion [2].

  • Pediatrician recommendations: Always start here. Your doctor may suggest supplements based on growth charts, feeding history, or lab tests.

Step 2: Understand the Most Common Baby Supplements

Here’s a breakdown of common baby supplements and what they do:

1. Vitamin D

Vitamin D helps babies absorb calcium for strong bones and immune support. The AAP recommends 400 IU daily for breastfed babies [3].

2. Probiotics

These are live bacteria that help support a healthy gut. Some research suggests probiotics can reduce colic, improve digestion, and help rebalance the microbiome after antibiotics [5].

3. Prebiotics

Prebiotics are fibers that feed the good bacteria in your baby’s gut. They’re naturally found in breastmilk (called HMOs, or Human Milk Oligosaccharides), and some formulas or supplements like Beginbaby Prebiotic + Probiotics now include them. They can help support softer stools, better digestion, and even immune health [6].

Step 3: Check the Ingredients (Less Is More)

For babies, simplicity matters. Choose supplements with minimal ingredients and avoid artificial colors, sugars, and unnecessary additives. 

Look for these qualities:

  • Clinically studied strains or ingredients (e.g., Bifidobacterium infantis or 2’-FL)

  • Age-appropriate dosing

  • Free from preservatives, sugar, or flavorings

  • Clear sourcing and safety testing

If a supplement feels like a long chemistry list, it’s okay to keep looking.

Step 4: Think About Ease and Consistency

Even the best baby supplement won’t help if your baby refuses it. That’s why many parents look for tasteless, textureless powders that mix easily into milk, formula, or food. Liquid droppers are also a popular option, but some parents find them harder to dose consistently.

Consistency is key! Many supplements like Beginbaby Prebiotic + Probiotics work best when taken daily.

Step 5: Ask Questions and Trust Your Instincts

You know your baby best. If something feels off, or if a supplement doesn’t seem to be working, don’t hesitate to switch or stop. And always bring any concerns to your pediatrician. Supplements are there to support you, not stress you out.

Summary

Choosing a baby supplement doesn’t have to be complicated. Focus on what your baby might actually need, look for high-quality and gentle ingredients, and keep it consistent. 

View Citation

  1. Rutayisire, E., Huang, K., Liu, Y., & Tao, F. (2016). The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life: A systematic review. BMC Gastroenterology, 16, 86. https://doi.org/10.1186/s12876-016-0498-0
  2. Closa-Monasterolo, R., Ferré, N., Luque, V., et al. (2017). Prebiotic supplementation improves stool consistency and frequency in children with functional constipation: A randomized controlled trial. Journal of Pediatric Gastroenterology and Nutrition, 64(4), 379–385. https://doi.org/10.1097/MPG.0000000000001346
  3. Wagner, C. L., & Greer, F. R. (2008). Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics, 122(5), 1142–1152. https://doi.org/10.1542/peds.2008-1862
  4. Baker, R. D., & Greer, F. R. (2010). Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children. Pediatrics, 126(5), 1040–1050. https://doi.org/10.1542/peds.2010-2576
  5. Szajewska, H., & Kolodziej, M. (2015). Systematic review with meta‐analysis: Saccharomyces boulardii in the prevention of antibiotic‐associated diarrhoea in children. Alimentary Pharmacology & Therapeutics, 42(7), 793–801. https://doi.org/10.1111/apt.13330
  6. Vandenplas, Y., De Greef, E., & Veereman, G. (2014). Prebiotics in infant formula. Gut Microbes, 5(6), 681–687. https://doi.org/10.4161/gmic.32191