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Begin Health's HMOs: How They Are Made and Sourced

Medically reviewed by Begin Nutrition Team | Published February 09, 2025

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Human Milk Oligosaccharides (HMOs)have gained significant attention for their role in supporting infant gut health, immune function, and overall well-being. 

Naturally found in breast milk, HMOs are a key component that nourishes beneficial gut bacteria, particularly Bifidobacterium infantis.

Given their importance, many parents wonder: How are HMOs made? Are they extracted from breast milk? Where does Begin Health source its HMOs?

Let’s break it down.

What Are HMOs and How Are They Made?

HMOs, or human milk oligosaccharides, are a type ofprebiotic carbohydrate naturally present in human breast milk.

While they resemble dietary fiber, their primary function is to act as food for beneficial gut bacteria.

Over 200 different HMOs have been identified, with 2’-Fucosyllactose (2’-FL) being one of the most studied.

To replicate the benefits of HMOs in infant nutrition and gut health supplements, scientists have developed a safe and ethical way toproduce bioidentical HMOs without using human breast milk

The most common method involves  precision fermentation, a process that uses specialized enzymes and microorganisms (such as Escherichia coli strains that are non-pathogenic) to produce HMOs that are structurally identical to those found in human milk.

Are Begin Health HMOs Extracted from Breast Milk?

No, commercially available HMOs are not extracted from human breast milk. 

Instead, they are made through fermentation using food-grade microorganisms. 

This method ensures that the production is ethical, scalable, and safe for widespread use while maintaining the same benefits as naturally occurring HMOs.

Where Does Begin Health Source Its HMOs?

Begin Health sources high-purity HMOs from trusted suppliers in Germany who use cutting-edge fermentation technology. These suppliers adhere to strict quality and safety standards to ensure the HMOs are safe, effective, and bioavailable for infants and kids. 

Read more about how we use third-party testing to ensure our products are safe and effective for your family. 

The production process includes rigorous purification and testing, ensuring that the final product is free from contaminants and structurally identical to naturally occurring HMOs.

Why Are HMOs Important for Gut Health?

HMOs serve several essential functions for infant and toddler gut health, including:

  1. Promoting Beneficial Gut Bacteria – HMOs selectively nourish beneficial bacteria, particularlyBifidobacterium infantis, which helps shape a healthy gut microbiome.

  2. Strengthening the Immune System – HMOs act asdecoy receptors, preventing harmful bacteria from attaching to the gut lining and reducing the risk of infections.

  3. Supporting Digestive Health – By fostering a balanced microbiome, HMOs helpsoften stools and promote regularity, making them especially beneficial for infants prone to constipation.

Summary 

HMOs are a groundbreaking innovation in infant and kid gut health, offering the benefits of breast milk without requiring human milk donations. 

Begin Health’s HMOs are sourced through safe and sustainable fermentation processes, ensuring parents can confidently support their little one's gut health.

View Citation

  1. Marcobal, A., & Sonnenburg, J. L. (2012). "Human Milk Oligosaccharide Consumption by Intestinal Microbiota." Clinical Microbiology and Infection, 18(Suppl 4), 12–15.
  2. Bode, L. (2012). "Human Milk Oligosaccharides: Every Baby Needs a Sugar Mama." Glycobiology, 22(9), 1147–1162.
  3. Vandenplas, Y., Berger, B., Carnielli, V. P., et al. (2020). "Human Milk Oligosaccharides and Their Role in the Development of the Gastrointestinal Tract in Infants." Nutrients, 12(5), 1331.